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- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
The drug was tested on mice on the International Space Station (ISS).
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
A new study reports the compound was engineered to help increase the formation of new bone material.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
The American space agency NASA has long studied the effects of space travel on human health.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Astronauts who have spent long periods in space have taken part in major studies that looked at their health before, during and after their trips, or
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
missions. NASA announced that American astronaut Frank Rubio recently set the agency’s record for the longest single spaceflight by a U.S.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
astronaut. Rubio, who is set to return to Earth on September 27, has spent 371 days in space.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
NASA astronaut Mark Vande Hei set the earlier record in March of 2022 after living in space for 355 days.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Some of the main health problems for humans are related to the gravitational conditions in space.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Past studies have shown the low gravity environments in space can greatly reduce or stop the formation of new bone material.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
NASA has estimated that astronauts spending more than six months in space can lose between six and 10 percent of bone matter.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Some experiments in astronauts measured changes in their upper leg.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Development of new bone can take at least three or four years after astronauts return to Earth, NASA says.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
The conditions astronauts experience in space can result in bone loss up to 10 times more than is seen in human patients dealing with the bone loss disease
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
osteoporosis, NASA notes. Currently, physical exercise is the main method astronauts use to reduce bone loss during long periods in space.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Generally, crew members aboard the ISS spend about 2.5 hours each day exercising in an effort to reduce the gravitational effects of space.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Past research on the subject has suggested a group of drugs widely used to treat osteoporosis, called bisphosphonates, have shown promise in Earth-based
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
experiments on bone loss. That research continues.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
But the new study shows success combining a bisphosphonate with another substance that has shown promise in helping to regrow bone material.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
That substance is called NELL-1. It was discovered by scientist Kang Ting at the Massachusetts-based Forsyth Institute.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
The study was led by a team from the University of California, Los Angeles (UCLA).
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
In a statement the research team said the resulting compound, a molecule called BP-NELL-PEG, was given to mice aboard the ISS to test its
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
effectiveness. The experiments were carried out by astronauts who arrived on the ISS in June 2017.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Half the mice remained on the ISS for nine weeks, while the rest were flown back to Earth four-and-a-half weeks after launch.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
Both sets of mice were given either BP-NELL-PEG or a salt solution containing no medicine.
- Public domaingeneral-american
Study: Drug Could Block Bone Loss in Astronauts in Space
The researchers reported both sets of mice who were given the BP-NELL-PEG compound showed “a significant increase in bone formation” during the
Source badges: Public domain · Creator video · Digital presenter · Reference recording. Literary passages are public domain. Studio notes are not spoken in the audio.