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- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The system also considers detailed biological and structural information related to the virus.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The method is a form of “generative AI,” a term describing technology tools designed to operate at human levels.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
EVEscape was developed by researchers from Britain’s University of Oxford and Harvard Medical School in Boston, Massachusetts.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The team’s findings recently appeared in a study in the publication Nature Many viruses repeatedly mutate in an effort to stay alive and strong.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
This requires viruses to infect living organisms. Once inside the body, viruses continue to reproduce and spread.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The U.S. Centers for Disease Control and Prevention (CDC) explains that repeated mutating creates new variants.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
Some of these mutations permit the virus “to spread more easily or make it resistant to treatments or vaccines,” the CDC said.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The researchers built on previous work involving a tool they created called EVE.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
This tool was designed to study gene mutations that can cause human disease.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
In a past study, the team said it successfully used EVE to identify mutations linked to conditions like cancer and heart disease.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
During the COVID-19 pandemic, the scientists said they recognized a good chance to “rebuild” EVE into a new tool “for the purpose of predicting viral
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
variants.” To do this, the team explained it “turned the clock back to January 2020, just before the COVID-19 pandemic started.”
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The researchers asked the EVEscape tool to predict what mutations would develop from the SARS-CoV-2 virus that causes COVID-19.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The researchers reported the tool correctly predicted which SARS-CoV-2 mutations would appear and which would become most common, or dominant.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The team also said the tool predicted which antibody-based treatments “would lose their efficacy as the pandemic progressed and the virus developed mutations to escape
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
these treatments.” The study noted EVEscape can make predictions more quickly and effectively than lab-based methods.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
This is because the tool does not need “to wait for relevant antibodies to arise in the population and become available for testing.”
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The team said the system was able to examine tens of thousands of new virus variants appearing each week and identified the ones most likely to become
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
problematic. Sarah Gurev is a student in the Electrical Engineering and Computer Science program at the Massachusetts Institute of Technoology (MIT).
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
She was a leader of the research. Gurev said that by quickly identifying the threat level of new variants, “we can help inform earlier public health decisions.”
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The team said it continuously uses the system to examine real-time data about the development of new variants of SARS-CoV-2.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
The researchers said their experiments also showed the EVEscape tool could successfully predict mutating behaviors for other common viruses, including HIV
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
and the flu. Debora Marks is a professor of systems biology at Harvard Medical School’s Blavatnik Institute.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
She was a lead writer of the study. She said the researchers would continue to improve the tool’s ability to predict new variants for a number of viruses.
- Public domaingeneral-american
AI Tool Aims to Predict Virus Variants before They Appear
“Because if we can, that’s going to be extremely important for designing vaccines and therapies I’m Bryan Lynn.
Source badges: Public domain · Creator video · Digital presenter · Reference recording. Literary passages are public domain. Studio notes are not spoken in the audio.